Harris Lab

In Pursuit of Synapse Structure and Function...

The Laboratory of Synapse Structure and Function investigates the structural basis of learning and memory, synapse development, and the ultrastructure of synaptic plasticity using in vivo and in vitro preparations, hippocampal slice physiology, serial section transmission electron microscopy, and 3D reconstruction.

Current Lab Members at UT Austin

	P.I.: Kristen M. Harris, Ph.D. Professor, Department of Neuroscience Center for Learning and Memory Institute for Neuroscience The University of Texas at Austin kharris@mail.clm.utexas.edu Kristen has served on the faculty of the Harvard Medical School, Boston University, and the Medical College of Georgia. She has been a Professor at UT Austin since 2006. More info and CV
	John Mendenhall, MA Research Associate jmenden@mail.utexas.edu John joined Kristen Harris's new lab at UT in 2006. His main responsibilities in the lab are tissue preparations, multi-dimensional imaging, visualization, and analysis.
	Masaaki (Masa) Kuwajima, Ph.D. Research Associate mkuwajima@mail.clm.utexas.edu Masa uses electron microscopy and immunolabeling methods to investigate subcellular structures that underlie brain cell functions in learning and memory, normal brain development, as well as in disease models. More info
	Lyndsey Kirk, Ph.D. Postdoctoral Fellow lyndskirk@utexas.edu Lyndsey is primarily interested in how synapses change with cognitive decline in aging. She uses a combination of animal behavior, genetics, physiology, and 3DEM to study the ultrastructural changes of synapses, astroglia, and subcellular organelles that occur and may contribute to loss of cognitive ability.
	Olga Ostrovskaya, Ph.D. Research Scientist islandsky@utexas.edu Olga's specialty is in electrophysiology. Her current focus is the dynamics of neuronal ultrastructure in the context of learning and memory across different developmental stages.
	Patrick Parker Research Assistant / Course Specialist patrickparker@mail.clm.utexas.edu Patrick assists in the 3D reconstruction of dendrites, with a focus on quantifying synapses and creating lab protocols to teach best uses of Reconstruct. He acts as the SynapseWeb administrator and Course Specialist for Prof. Harris's class.
	Dakota Hanka Research Assistant dakotahanka@utexas.edu Dakota aids in the 3D reconstruction and quantification of dendrites, axons, and other neuropil objects. His focuses are data collection, analysis, and developmental testing of new computational tools used in the lab.
	Dusten Hubbard Research Assistant dusten@utexas.edu Dusten aids in the 3D reconstruction and quantification of dendrites, axons, and other neuropil objects. His focuses are data collection, analysis, and developmental testing of new computational tools used in the lab.
	Anna-Maria E. Escherich, MS, PMP Project Manager/Lab Manager amescherich@austin.utexas.edu Anna-Maria is actively involved with the oversight of the NeuroNex NSF grant, as well as other NIH-awarded grants in the Harris Lab. In addition, Anna-Maria is involved in overseeing the day-to-day operations of the lab.